Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections
Yasin Kurmoo, Andrew L. Hook, Daniel Harvey, Jean‐Frédéric Dubern, Paul Williams, Stephen P. Morgan, Sergiy Korposh, Morgan R. Alexander
Abstract
, by comparison with the confocal image quantification. An empirical exponential function was found to link the optical attenuation wavelength shift with the inverse of the biofilm biomass, allowing quantification of biofouling from the spectral response. Quantification from the sensor allows infection interception and early device removal, to reduce, for example, the risk of ventilator associated pneumonia.
Topics & Concepts
BiofilmInterceptionReduction (mathematics)MicrobiologyChemistryBacteriaBiologyEcologyMathematicsGeometryGeneticsBacterial biofilms and quorum sensingInhalation and Respiratory Drug DeliveryNosocomial Infections in ICU