Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy
Kathryn McCauley, Elze Rackaityte, Brandon LaMere, Douglas Fadrosh, Kei E. Fujimura, Ariane Panzer, Din L. Lin, Kole Lynch, Joanna Halkias, Ventura F. Mendoza, Trevor D. Burt, Casper G. Bendixsen, Kathrine L. Barnes, Hae Jin Kim, Kyra Jones, Dennis R. Ownby, Christine Cole Johnson, Christine M. Seroogy, James E. Gern, Homer A. Boushey, Susan V. Lynch
Abstract
T cells. Thus, bacterial and atopy heritability are intimately linked, suggesting a microbial component of intergenerational disease transmission.
Topics & Concepts
AtopyImmunologyBiologyImmunoglobulin EAllergyAsthmaImmune systemMicrobiologyAntibodyGut microbiota and healthReproductive tract infections researchAsthma and respiratory diseases