Synthesis and Screening of New [1,3,4]Oxadiazole, [1,2,4]Triazole, and [1,2,4]Triazolo[4,3-<i>b</i>][1,2,4]triazole Derivatives as Potential Antitumor Agents on the Colon Carcinoma Cell Line (HCT-116)
El-Sayed M. Abdelrehim
Abstract
exhibited moderate cytotoxic activity.
Topics & Concepts
ChemistryChloroacetic acid1,2,4-TriazoleOxadiazoleHydrazideMorpholineTriazoleHydrazine (antidepressant)FormaldehydeMedicinal chemistry1,2,3-TriazoleCombinatorial chemistryOrganic chemistryChromatographySynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsClick Chemistry and Applications