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In situ mechanical reinforcement of polymer hydrogels via metal-coordinated crosslink mineralization

Sungjin Kim, Abigail U. Regitsky, Jake Song, Ján Ilavský, Gareth H. McKinley, Niels Holten‐Andersen

2021Nature Communications150 citationsDOIOpen Access PDF

Abstract

Biological organic-inorganic materials remain a popular source of inspiration for bioinspired materials design and engineering. Inspired by the self-assembling metal-reinforced mussel holdfast threads, we tested if metal-coordinate polymer networks can be utilized as simple composite scaffolds for direct in situ crosslink mineralization. Starting with aqueous solutions of polymers end-functionalized with metal-coordinating ligands of catechol or histidine, here we show that inter-molecular metal-ion coordination complexes can serve as mineral nucleation sites, whereby significant mechanical reinforcement is achieved upon nanoscale particle growth directly at the metal-coordinate network crosslink sites.

Topics & Concepts

Self-healing hydrogelsMaterials scienceMetalPolymerNucleationMineralization (soil science)Composite numberAqueous solutionNanotechnologyIn situChemical engineeringPolymer chemistryComposite materialChemistryOrganic chemistryMetallurgyNitrogenEngineeringBone Tissue Engineering MaterialsCalcium Carbonate Crystallization and InhibitionPolymer Surface Interaction Studies
In situ mechanical reinforcement of polymer hydrogels via metal-coordinated crosslink mineralization | Litcius