Litcius/Paper detail

New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation

Yingying Zheng, Li Lu, Mengyue Li, DeHua Xu, LaiShun Zhang, Zhuang Xiong, Yubo Zhou, Jia Li, Xuetao Xu, Kun Zhang, Lei Xu, Kun Zhang, Lei Xu

2023Bioorganic Chemistry20 citationsDOI

Topics & Concepts

ChemistryMoietyChromoneThiazolidineStereochemistryDocking (animal)IC50Lead compoundBiological activityStructure–activity relationshipPalmitic acidIn vitroBiochemistryFatty acidMedicineNursingSynthesis of Organic CompoundsProtein Tyrosine PhosphatasesCarbohydrate Chemistry and Synthesis
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation | Litcius