Epigenetically modifying the Foxp3 locus for generation of stable antigen-specific Tregs as cellular therapeutics
Shuqiu Chen, Lei Zhang, Yuanlin Ying, Yixuan Wang, Preston R. Arnold, Guangchuan Wang, Junhui Li, R. Mark Ghobrial, Wenhao Chen, Xiang Xiao, Li X
Topics & Concepts
FOXP3ImmunologyAutoimmunityEx vivoTransplantationIn vivoBiologyMedicineCancer researchImmune systemGeneticsSurgeryT-cell and B-cell ImmunologyImmune Cell Function and InteractionCAR-T cell therapy research