Design, synthesis, docking study, cytotoxicity evaluation, and PI3K inhibitory activity of Novel di-thiazoles, and bis(di-thiazoles)
Mostafa E. Salem, Mohamed Samir, Ahmed H. M. Elwahy, Ahmad M. Farag, Abdelfattah Selim, Aiman Alsaegh, Marwa Sharaky, Noha Bagato, Ibrahim Taha Radwan
Topics & Concepts
ChemistryThiazoleIC50CytotoxicityStereochemistryEnzymeDocking (animal)Hydrogen bondCombinatorial chemistryIn vitroBiochemistryOrganic chemistryMoleculeNursingMedicineSynthesis and biological activityQuinazolinone synthesis and applicationsCancer Mechanisms and Therapy