Dynamic analysis of <i>Porphyromonas gingivalis</i> invasion into blood capillaries during the infection process in host tissues using a vascularized three-dimensional human gingival model
Naoko Sasaki, Hiroki Takeuchi, Shiro Kitano, Shinji Irie, Atsuo Amano, Michiya Matsusaki
Abstract
invasion from the epithelial cell layer into the blood capillaries for the first time, this model will be a powerful tool for the development of novel therapeutics against periodontal infection related diseases.
Topics & Concepts
Porphyromonas gingivalisUmbilical veinFibroblastCellHuman umbilical vein endothelial cellChemistryMicrobiologyCell culturePathologyCell biologyBiologyPeriodontitisMedicineDentistryIn vitroGeneticsBiochemistryOral microbiology and periodontitis researchPeriodontal Regeneration and TreatmentsProteoglycans and glycosaminoglycans research