Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis
Yi Fu, Olivia Sacco, Emily DeBitetto, Evgeny Kanshin, Beatrix Ueberheide, Agnel Sfeir
Topics & Concepts
BiologyHomeostasisCell biologyMitochondrial DNAMitochondrionFight-or-flight responseDNA damageDNAGeneticsGeneMitochondrial Function and PathologyEndoplasmic Reticulum Stress and DiseaseMetabolism and Genetic Disorders