Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier
Ram Sharma, Esha Chatterjee, Jacob Mathew, Sachin Sharma, N. Vijayakameswara Rao, Chun Pan, Sung‐Bau Lee, Ashwani K. Dhingra, Ajmer Singh Grewal, Jing‐Ping Liou, Santosh Kumar Guru, Kunal Nepali
Topics & Concepts
ChemistryPharmacophoreNanocarriersRing (chemistry)StereochemistryInhibitory postsynaptic potentialLung cancerAccommodationPharmacologyCombinatorial chemistryDrug deliveryOrganic chemistryOncologyNeuroscienceMedicineBiologyHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisCancer therapeutics and mechanisms