Inhibition of SARS-CoV-2 main protease: a repurposing study that targets the dimer interface of the protein
Hanife Pekel, Metehan Ilter, Özge Şensoy
Abstract
Communicated by Ramaswamy H. Sarma.
Topics & Concepts
RepurposingChemistryProteaseDrug repositioningDimerComputational biologySmall moleculeDrug discoveryBiophysicsStereochemistryBiochemistryEnzymeBiologyDrugPharmacologyEcologyOrganic chemistryComputational Drug Discovery MethodsProtein Structure and DynamicsSynthesis and biological activity