New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells
Diones Bueno, Rômulo Faria Santos Canto, Viviane de Souza, Rafaela Rafognatto Andreguetti, Flavio A. R. Barbosa, Aline Aita Naime, Partha Narayan Dey, Verena Wüllner, Mark William Lopes, Antônio L. Braga, Axel Methner, Marcelo Farina
Topics & Concepts
ProbucolNeuroprotectionGlutathione peroxidaseGlutathioneChemistryPharmacologyGlutamate receptorGPX4MitochondrionIn vivoProgrammed cell deathSuperoxideBiochemistryAntioxidantBiologyApoptosisEnzymeBiotechnologyReceptorCholesterol and Lipid MetabolismFerroptosis and cancer prognosisDrug Transport and Resistance Mechanisms