ROS/TGF-β signal mediated accumulation of SOX4 in OA-FLS promotes cell senescence
Xiaokang Ye, Chunlai Yin, Xinxin Huang, Yifan Huang, Lu Ding, Minli Jin, Zhen Wang, Jing Wei, Xia Li
Topics & Concepts
SenescencePathogenesisTransforming growth factorTranscription factorSOX4InflammationBiologyImmunologyMedicineCancer researchCell biologyGene expressionGeneGeneticsPromoterNF-κB Signaling PathwaysOsteoarthritis Treatment and Mechanismsinterferon and immune responses