From Seeds of<i>Apium graveolens</i>Linn. to a Cerebral Ischemia Medicine: The Long Journey of 3-<i>n</i>-Butylphthalide
José Marco‐Contelles, Yihua Zhang
Abstract
3-n-Butylphthalide (NBP) as well as its derivatives and analogues (NBPs), in racemic or enantiomerically pure forms, possess potent and diverse pharmacological properties and have shown a great potential therapeutic interest for many human conditions, especially for cerebral ischemia. This Perspective outlines the synthesis and therapeutic applications of NBPs.
Topics & Concepts
ChemistryApium graveolensCerebral ischaemiaIschemiaPharmacologyTraditional medicineStereochemistryBotanyInternal medicineMedicineBiologyNeurological Disease Mechanisms and TreatmentsNeurological Disorders and TreatmentsTraditional Chinese Medicine Analysis