Targeted IL-4Rα blockade ameliorates refractory allergic eosinophilic inflammation in a patient with dysregulated TGF-β signaling due to ERBIN deficiency
Harris Richard Droghini, J. Pablo Abonia, Margaret H. Collins, Joshua D. Milner, Jonathan J. Lyons, Alexandra F. Freeman, Vincent A. Mukkada, Kimberly Risma, Marc E. Rothenberg, Justin T. Schwartz
Topics & Concepts
MedicineAtopyImmunologyBlockadeTransforming growth factor betaTransforming growth factorImmunotherapyInflammationInterleukin 13Signal transductionEosinophilAllergyInterleukinCancer researchReceptorCytokineImmune systemInternal medicineAsthmaBiologyBiochemistryEosinophilic EsophagitisEosinophilic Disorders and SyndromesIL-33, ST2, and ILC Pathways