Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
Theresa Klemm, Gregor Ebert, Dale J. Calleja, Cody C. Allison, Lachlan W. Richardson, Jonathan P. Bernardini, Bernadine G.C. Lu, Nathan W. Kuchel, Christoph Grohmann, Y. Shibata, Zhong Yan Gan, James P. Cooney, Marcel Doerflinger, Amanda E. Au, T. Blackmore, Gerbrand J. van der Heden van Noort, Paul P. Geurink, Huib Ovaa, Janet Newman, Alan Riboldi‐Tunnicliffe, Peter E. Czabotar, Jeffrey P. Mitchell, Rebecca Feltham, Bernhard C. Lechtenberg, Kym N. Lowes, Grant Dewson, Marc Pellegrini, Guillaume Lessène, David Komander
Topics & Concepts
ISG15BiologyUbiquitinProteaseProteasesBiochemistryPapainDeubiquitinating enzymeProteolysisVirologyEnzymeGeneinterferon and immune responsesNF-κB Signaling Pathwaysvaccines and immunoinformatics approaches