Antiproliferative effect, alteration of cancer cell cycle progression and potential MET kinase inhibition induced by 3,4-dihydropyrimidin-2(1H)-one C5 amide derivatives
Fatemeh Moosavi, Ahmad Ebadi, Maryam Mohabbati, Tahereh Damghani, Motahareh Mortazavi, Ramin Miri, Omidreza Firuzi
Topics & Concepts
ApoptosisCancer cellCell cycleReceptor tyrosine kinaseCell growthCell cycle checkpointChemistryCancer researchMTT assayCell cultureKinaseCancerGrowth inhibitionTyrosine kinasePharmacologyReceptorBiologyBiochemistryMedicineInternal medicineGeneticsSynthesis and biological activityCancer Mechanisms and TherapySynthesis and Characterization of Heterocyclic Compounds