A highly selective and sensitive endoplasmic reticulum-targeted probe reveals HOCl- and cisplatin-induced H<sub>2</sub>S biogenesis in live cells
Haishun Ye, Shanshan Liu, Ziyi Chen, Longhuai Cheng, Long Yi
Abstract
A highly selective and sensitive, endoplasmic reticulum (ER)-targeted fluorescent probe was successfully developed and applied to reveal HOCl- and cisplatin-induced H 2 S biogenesis in live cells.
Topics & Concepts
Endoplasmic reticulumBiogenesisCisplatinCell biologyChemistryFluorescenceBiologyBiochemistryGeneGeneticsPhysicsChemotherapyQuantum mechanicsSulfur Compounds in BiologyHeme Oxygenase-1 and Carbon MonoxideNeuroscience of respiration and sleep