The protective effect of 5-O-methylvisammioside on LPS-induced depression in mice by inhibiting the over activation of BV-2 microglia through Nf-κB/IκB-α pathway
Xialin Sun, Tingwen Zhang, Yan Zhao, Enbo Cai, Hongyan Zhu, Shuangli Liu
Topics & Concepts
MicrogliaTumor necrosis factor alphaLipopolysaccharideHippocampusPharmacologyWestern blotChemistryNeuroprotectionNF-κBNitric oxideEndocrinologyImmunologyInflammationInternal medicineMedicineBiochemistryGeneTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsAlkaloids: synthesis and pharmacology