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Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial

Keith J. Chappell, Francesca L. Mordant, Zheyi Li, Danushka K. Wijesundara, Paula Ellenberg, Julia Lackenby, Stacey T. M. Cheung, Naphak Modhiran, Michael S. Avumegah, Christina L Henderson, Kym Hoger, Paul Griffin, Jillian Bennet, Luca Hensen, Wuji Zhang, Thi H. O. Nguyen, Sara Marrero‐Hernández, Kevin J. Selva, Amy W. Chung, Mai H. Tran, Peter Tapley, James Barnes, Patrick C. Reading, Suellen Nicholson, Stavroula Corby, Thomas Holgate, Bruce D. Wines, P. Mark Hogarth, Katherine Kedzierska, Damian F. J. Purcell, Charani Ranasinghe, Kanta Subbarao, Daniel Watterson, Paul R. Young, Trent P. Munro

2021The Lancet Infectious Diseases121 citationsDOIOpen Access PDF

Topics & Concepts

MedicinePlaceboImmunogenicityAdverse effectClinical trialRandomized controlled trialImmunologyInternal medicineVirologyAntibodyPathologyAlternative medicineSARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesCOVID-19 Clinical Research Studies
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial | Litcius