Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
Rosemarie Ungricht, Laure Guibbal, Marie-Christine Lasbennes, Vanessa Orsini, Martin Beibel, Annick Waldt, Rachel Cuttat, Walter Carbone, Anne Basler, Guglielmo Roma, Florian Nigsch, Jan S. Tchorz, Dominic Hoepfner, Philipp S. Hoppe
Topics & Concepts
BiologyInduced pluripotent stem cellOrganoidCRISPRKidney developmentComputational biologyGenomeGeneticsGeneEmbryonic stem cellRenal and related cancersGenetic and Kidney Cyst DiseasesRenal cell carcinoma treatment