NSUN6 inhibitor discovery guided by its mRNA substrate bound crystal structure
Fumei Zhong, Pu Tian, Qian Hu, Mingwei Li, Lei Wang, Suman Wang, Ke Ruan, Yunyu Shi, Beicheng Sun, Yiyang Jiang, Mengqi Lv
Topics & Concepts
ChemistryComputational biologySubstrate (aquarium)Messenger RNABiophysicsCrystallographyCell biologyBiologyBiochemistryGeneEcologyEnzyme Structure and FunctionRNA and protein synthesis mechanismsGlycosylation and Glycoproteins Research