Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ1–42 through inhibiting RhoA/ROCK2 pathway
Xiaotong Xiang, Xin Wang, Shiyu Jin, Jie Hu, Yumei Wu, Yueyue Li, Xian Wu
Topics & Concepts
NeurotoxicityMorris water navigation taskRHOASynaptophysinSuperoxide dismutaseHippocampusChemistryMalondialdehydePharmacologyEndocrinologyInternal medicineMedicineOxidative stressBiochemistrySignal transductionToxicityImmunohistochemistryAlzheimer's disease research and treatmentsNeuroscience and Neuropharmacology ResearchNeuropeptides and Animal Physiology