The different effects of psyllium husk and orlistat on weight control, the amelioration of hypercholesterolemia and non-alcohol fatty liver disease in obese mice induced by a high-fat diet
Zhitong Deng, Cong Meng, Haodong Huang, Siyu Song, Linchun Fu, Zhuotao Fu
Abstract
, which led to the difference in the serum lipopolysaccharide (LPS) level. Orlistat increased the food intake of the obese mice that were fed a HFD, which led to an increase in water intake, serum triglyceride levels, and lower glucose tolerance. Although orlistat is considered a suitable drug for weight loss, psyllium husk is a comparatively more cost-effective choice for ameliorating hypercholesterolemia and non-alcoholic fatty liver disease caused by a HFD.
Topics & Concepts
OrlistatPsylliumHuskCholesterolObesityFatty liverMedicineAlcoholHyperlipidemiaFood scienceInternal medicineChemistryEndocrinologyDiseaseWeight lossBiochemistryBiologyDiabetes mellitusDietary fiberBotanyLipid metabolism and biosynthesisCholesterol and Lipid MetabolismLiver Disease Diagnosis and Treatment