The mutation of SPI51, a protease inhibitor of silkworm, resulted in the change of antifungal activity during domestication
Xiaolu Zhang, Yu-Hui Ni, Kaiyu Guo, Zhaoming Dong, Yuqing Chen, Hongtao Zhu, Qingyou Xia, Ping Zhao
Topics & Concepts
ProteaseBiologyProtease inhibitor (pharmacology)Active siteGeneAntifungalBiochemistryMutationDomesticationFunction (biology)Peptide sequenceMutantEnzymeGeneticsMolecular biologyMicrobiologyViral loadVirusAntiretroviral therapySilk-based biomaterials and applicationsInvertebrate Immune Response MechanismsNeurobiology and Insect Physiology Research