Allylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines
Qiang Cheng, Junting Chen, Songyun Lin, Tobias Ritter
Abstract
Allylic C-H amination is currently accomplished with (sulfon)amides or carbamates. Here we show the first allylic amination that can directly afford alkyl allylamines, enabled by the reactivity of thianthrene-based nitrogen sources that can be prepared from primary amines in a single step.
Topics & Concepts
Allylic rearrangementAminationChemistryReactivity (psychology)AlkylOrganic chemistryMedicinal chemistryCatalysisMedicineAlternative medicinePathologySynthesis and Catalytic ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques