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Pseudoephedrine—Benefits and Risks

Krystyna Głowacka, Anna Wiela−Hojeńska

2021International Journal of Molecular Sciences56 citationsDOIOpen Access PDF

Abstract

Pseudoephedrine (PSE) is a drug with a long history of medical use; it is helpful in treating symptoms of the common cold and flu, sinusitis, asthma, and bronchitis. Due to its central nervous system (CNS) stimulant properties and structural similarity to amphetamine, it is also used for non-medical purposes. The substance is taken as an appetite reducer, an agent which eliminates drowsiness and fatigue, to improve concentration and as a doping agent. Due to its easier availability, it is sometimes used as a substitute for amphetamine or methamphetamine. Pseudoephedrine is also a substrate (precursor) used in the production of these drugs. Time will tell whether legal restrictions on the sale of this drug will reduce the scale of the problem associated with its misuse.

Topics & Concepts

PseudoephedrineStimulantMethamphetamineAmphetamineMedicineEphedrineDrugNasal decongestantPharmacologyIntensive care medicineAnesthesiaInternal medicineDopaminePharmacology and Obesity TreatmentAnalytical Methods in PharmaceuticalsDiet and metabolism studies
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