The miR-182/Myadm axis regulates hypoxia-induced pulmonary hypertension by balancing the BMP- and TGF-β-signalling pathways in an SMC/EC-crosstalk-associated manner
Yongyi Bai, Jingrong Wang, Ying Chen, Tingting Lv, Xiaojian Wang, Chunlei Liu, Hao Xue, Kunlun He, Lan Sun
Topics & Concepts
CrosstalkBone morphogenetic proteinGene knockdownSignal transductionCell biologyTransforming growth factorBMPR2BiologyCancer researchProgenitor cellHedgehog signaling pathwayHypoxia (environmental)Downregulation and upregulationInternal medicineEndocrinologyStem cellChemistryMedicineCell cultureGeneOrganic chemistryBiochemistryOxygenOpticsPhysicsGeneticsPulmonary Hypertension Research and TreatmentsNeonatal Respiratory Health ResearchMicroRNA in disease regulation