Improved Overall Survival of Colorectal Cancer under Multidisciplinary Team: A Meta‐Analysis
Dong Peng, Yu-Xi Cheng, Yong Cheng
Abstract
Purpose . The purpose of the current meta‐analysis was to evaluate whether multidisciplinary team improved overall survival of colorectal cancer. Methods . PubMed, EMBASE, and Cochrane Library database were searched from inception to October 25, 2020. The hazard ratio (HR) and 95% confidence (CI) of overall survival (OS) were calculated. Results . A total of 11 studies with 30814 patients were included in this meta‐analysis. After pooling the HRs, the MDT group was associated with better OS compared with the non‐MDT group (HR = 0.81, 95% CI 0.69‐0.94, p = 0.005). In subgroup analysis of stage IV colorectal cancer, the MDT group was associated with better OS as well (HR = 0.73, 95% CI 0.59‐0.90, p = 0.004). However, in terms of postoperative mortality, no significant difference was found between MDT and non‐MDT groups (OR = 0.84, 95% CI 0.44‐1.61, p = 0.60). Conclusion . MDT could improve OS of colorectal cancer patients.