Photocatalytic Aerobic Coupling of Azaarenes and Alkanes via Nontraditional Cl^•Generation

Abstract

Herein, we demonstrate a nonconventional photocatalytic generation of Cl• from a common chlorinated solvent, dichloroethane, under aerobic conditions and its successful utilization toward the cross-dehydrogenative coupling of alkanes and azaarenes via hydrogen atom transfer with Cl•. The process is free from chloride salt, toxic oxidant, and UV light. It is applicable to a broad spectrum of substrates. The proposed mechanism involving Cl• is supported by a series of mechanistic investigations.

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