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Photocatalytic C–N cross-coupling mediated by heterogeneous nickel-coordinated carbon nitride

Qi Zhu, En Zhao, Yajing Shen, Zupeng Chen, Weiwei Fang

2023Organic & Biomolecular Chemistry13 citationsDOI

Abstract

An easy to prepare nickel-coordinated mesoporous graphitic carbon nitride (Ni-mpg-CN) was introduced as a heterogeneous photocatalyst, which efficiently accelerated the photocatalytic C-N cross-coupling of (hetero)aryl bromides and aliphatic amines, delivering the desired monoaminated products in good yields. In addition, the concise synthesis of the pharmaceutical tetracaine was accomplished in the final stage, further highlighting the practical applicability.

Topics & Concepts

PhotocatalysisNickelGraphitic carbon nitrideCarbon nitrideMesoporous materialNitrideMaterials scienceCoupling (piping)ArylCarbon fibersChemical engineeringCoupling reactionCatalysisNanotechnologyCombinatorial chemistryChemistryMetallurgyOrganic chemistryComposite materialLayer (electronics)EngineeringComposite numberAlkylAdvanced Photocatalysis TechniquesCatalytic C–H Functionalization MethodsRadical Photochemical Reactions
Photocatalytic C–N cross-coupling mediated by heterogeneous nickel-coordinated carbon nitride | Litcius