Benzoylaconine Modulates LPS-Induced Responses Through Inhibition of Toll-Like Receptor-Mediated NF-κB and MAPK Signaling in RAW264.7 Cells
Changkai Zhou, Jing Gao, Hongyan Ji, Wenjing Li, Xiaomin Xing, Donghua Liu, Qie Guo, Lihua Zhou, Fanbo Jing
Topics & Concepts
TLR4MAPK/ERK pathwayPhosphorylationp38 mitogen-activated protein kinasesNF-κBToll-like receptorSignal transductionCell biologyIκBαChemistryReceptorTumor necrosis factor alphaLipopolysaccharideBlotKinaseProinflammatory cytokineNFKB1InflammationMolecular biologyBiologyImmunologyBiochemistryInnate immune systemTranscription factorGeneNF-κB Signaling PathwaysNatural product bioactivities and synthesisImmune Response and Inflammation