Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy
Yoonjeong Jang, Yoon‐Sang Kim, Matthew M. Wielgosz, Francesca Ferrara, Zhijun Ma, Jose Condori, Lance E. Palmer, Xiwen Zhao, Guolian Kang, David J. Rawlings, Sheng Zhou, Byoung Y. Ryu
Topics & Concepts
Transduction (biophysics)Genetic enhancementStem cellHaematopoiesisCD34BiologyViral vectorHematopoietic stem cellGene deliveryXenotransplantationCell biologyImmunologyCancer researchTransplantationMedicineGeneGeneticsInternal medicineBiochemistryRecombinant DNAVirus-based gene therapy researchCRISPR and Genetic EngineeringCAR-T cell therapy research