Litcius/Paper detail

Inflammation and metabolism gene sets in subcutaneous abdominal adipose tissue are altered 1 hour after exercise in adults with obesity

Alison C. Ludzki, Michael W. Schleh, Emily M. Krueger, N. Taylor, Benjamin J. Ryan, Timothy C. Baldwin, Jenna B. Gillen, Changhwan Ahn, Pramod K. Varshney, Jeffrey F. Horowitz

2021Journal of Applied Physiology12 citationsDOIOpen Access PDF

Abstract

This study compared the effects of a single session of high-intensity interval exercise versus moderate-intensity continuous exercise on transcriptional changes in subcutaneous abdominal adipose tissue collected from adults with obesity. Our novel findings indicate exercise upregulated inflammation-related gene sets, while it downregulated metabolism-related gene sets - after both high-intensity and moderate-intensity exercise. These data suggest exercise can alter the adipose tissue transcriptome 1 h after exercise in ways that may impact inflammation and metabolism.

Topics & Concepts

Adipose tissueInflammationObesityMedicineEndocrinologyInternal medicineSubcutaneous fatSubcutaneous adipose tissueMetabolismPhysical exercisePhysiologyAdipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity