Uric Acid Mitigates Cognitive Deficits via TFEB-Mediated Microglial Autophagy in Mice Models of Alzheimer’s Disease
Qian Xiao, Jiaojiao Wang, Qiuyun Tian, Na Tian, Qi Tian, Xin He, Yutian Wang, Zhifang Dong
Topics & Concepts
AutophagyNeuroprotectionMorris water navigation taskGenetically modified mouseMicrogliaTFEBPharmacologyChemistryTransgeneNeuroscienceMedicineHippocampusBiologyInternal medicineBiochemistryInflammationGeneApoptosisAlzheimer's disease research and treatmentsTryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms