Flexible silk-fibroin-based microelectrode arrays for high-resolution neural recording
Jie Ding, Mingze Zeng, Yuan Tian, Zhihong Chen, Zi Qiao, Zhanwen Xiao, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan
Abstract
Ω. Experimental validation confirmed the superior electrophysiological signal recording capabilities of the SF-based MEA (SMEA) in peripheral and cerebral nerves with a much higher signal-to-noise ratio (SNR) of 20. In particular, we achieved high-precision recording of the action potential (AP) induced by flash visual stimulation, demonstrating high performance in weak signal recording. In summary, the development of SMEA provides a robust foundation for future investigations into the mechanisms and principles of neural circuit information transmission in complex nervous systems.
Topics & Concepts
MicroelectrodeFibroinMaterials scienceNanotechnologyNeural activityHigh resolutionMultielectrode arrayBiomedical engineeringNeuroscienceSILKChemistryBiologyMedicineElectrodeRemote sensingComposite materialGeologyPhysical chemistryNeuroscience and Neural EngineeringAdvanced Sensor and Energy Harvesting MaterialsConducting polymers and applications