ROS-responsive phenylboronic ester-based nanovesicles as multifunctional drug delivery systems for the treatment of inflammatory and thrombotic complications
Yu Xia, Runhai Chen, Yue Ke, Qiaoyi Han, Zhifang Ma, Qiang Shi
Abstract
mouse model of carrageenan tail thrombosis. Therefore, drug-delivery nanovesicles play multiple roles in the treatment of inflammation-induced thrombotic disorders, which offer a promising treatment for inflammatory and thrombotic complications.
Topics & Concepts
ChemistryDrugDrug deliveryEthylene glycolPharmacologyIn vivoAmphiphileInflammationTargeted drug deliveryPhenylboronic acidThrombusDrug carrierCombinatorial chemistryBiochemistryMedicineCopolymerOrganic chemistryImmunologyPolymerSurgeryBiologyCatalysisBiotechnologyNanoplatforms for cancer theranosticsExtracellular vesicles in diseaseNeutrophil, Myeloperoxidase and Oxidative Mechanisms