Integrative Genome-Scale Metabolic Modeling Reveals Versatile Metabolic Strategies for Methane Utilization in Methylomicrobium album BG8
Juan C. Villada, Maria F. Duran, Chee Kent Lim, Lisa Y. Stein, Patrick K. H. Lee
Abstract
A genome-scale metabolic model (GEM) is an integrative platform that enables the incorporation of a wide range of experimental data. It is used to reveal system-level metabolism and, thus, clarify the link between the genotype and phenotype.
Topics & Concepts
GenomePhenotypeComputational biologyBiologyMetabolic pathwayScale (ratio)GeneGeneticsPhysicsQuantum mechanicsMicrobial metabolism and enzyme functionMicrobial Metabolic Engineering and BioproductionBiofuel production and bioconversion