Litcius/Paper detail

BCR selection and affinity maturation in Peyer’s patch germinal centres

Huan Chen, Yuxiang Zhang, Adam Yongxin Ye, Zhou Du, Mo Xu, Cheng‐Sheng Lee, Joyce K. Hwang, Nia Kyritsis, Zhaoqing Ba, Donna Neuberg, Dan R. Littman, Frederick W. Alt

2020Nature119 citationsDOIOpen Access PDF

Topics & Concepts

Somatic hypermutationbreakpoint cluster regionBiologyGerminal centerAffinity maturationPeyer's patchB-cell receptorComplementarity determining regionSomatic cellGermlineImmunoglobulin heavy chainAntibodyGeneticsB cellAntigenImmunoglobulin light chainImmunologyGeneT-cell and B-cell ImmunologyImmune Cell Function and InteractionDiabetes and associated disorders