Nordihydroguaiaretic acid reverses the antibacterial activity of colistin against MCR-1-positive bacteria in vivo/in vitro by inhibiting MCR-1 activity and injuring the bacterial cell membrane
Ge Song, Yonglin Zhou, Sen Niu, Xuming Deng, Jiazhang Qiu, Li Li, Jianfeng Wang
Topics & Concepts
ColistinNordihydroguaiaretic acidPolymyxinIn vivoMicrobiologyPolymyxin BBacteriaPharmacologyMCR-1Antibacterial activityBiologyEnterobacteriaceaeAntibioticsAntibacterial agentChemistryEscherichia coliBiochemistryBiotechnologyEnzymeGeneticsGeneArachidonic acidAntibiotic Resistance in BacteriaMicrobial Natural Products and BiosynthesisImmune Response and Inflammation