Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancer
Si Ha, Changwei Ji, Jiaqi Yang, Maoxu Xiao, Ziyi Xu, Weiwei Pan, Hua Xiang, Guoshun Luo
Topics & Concepts
ChemistryProstate cancerCancerProstateTerminal (telecommunication)Cancer researchStereochemistryPharmacologyInternal medicineComputer scienceBiologyTelecommunicationsMedicineProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysProstate Cancer Treatment and Research