Neuroimaging of Germinal Matrix and Intraventricular Hemorrhage in Premature Infants
Sun Kyoung You
Abstract
Germinal matrix and intraventricular hemorrhage (GM-IVH) are the major causes of intracranial hemorrhage in premature infants. Cranial ultrasound (cUS) is the imaging modality of choice for diagnosing and classifying GM-IVH. Magnetic resonance imaging (MRI), usually performed at term-equivalent age, is more sensitive than cUS in identifying hemorrhage in the brain. Post-hemorrhagic ventricular dilatation is a significant complication of GM-IVH and correlates with adverse neurodevelopmental outcomes. In this review, we discuss the various imaging findings of GM-IVH in premature infants, focusing on the role of cUS and MRI.
Topics & Concepts
MedicineIntraventricular hemorrhageGerminal matrixNeuroimagingMagnetic resonance imagingRadiologyCardiologyGestational agePsychiatryPregnancyBiologyGeneticsNeonatal and fetal brain pathologyNeonatal Respiratory Health ResearchCerebrospinal fluid and hydrocephalus