Reduction of inflammation in a chronic periodontitis model in rats by TNF-α gene silencing with a topically applied siRNA-loaded calcium phosphate paste
Taichi Tenkumo, Leonardo Rojas‐Sánchez, Juan Ramón Vanegas Sáenz, Toru Ogawa, Makiko Miyashita, Nobuhiro Yoda, Oleg Prymak, Viktoriya Sokolova, Keiichi Sasaki, Matthias Epple
Topics & Concepts
In vivoGene silencingCalciumAlkaline phosphataseTumor necrosis factor alphaSmall interfering RNAInflammationIn vitroMaterials sciencePeriodontitisChemistryBiophysicsMolecular biologyBiochemistryTransfectionMedicineImmunologyEnzymeBiologyInternal medicineGeneMetallurgyBiotechnologyRNA Interference and Gene DeliveryNanoplatforms for cancer theranosticsOral microbiology and periodontitis research