A Preliminary Investigation of Genetic Variants Linked to Aripiprazole-Induced Adverse Effects
Katarzyna Guzek, Adriana Stelmach, Alicja Rożnowska, Irena Najbar, Łukasz Cichocki, Anna Sadakierska- Chudy
Abstract
The hepatic enzymes CYP2D6 and CYP3A4 are primarily accountable for the transformation of the atypical antipsychotic medication aripirazole. It is recommended that CYP2D6-poor metabolizers adjust their dosage. Most adult patients handle aripiprazole well; however, occasionally, some people may experience negative side effects that lead to the medication being stopped. According to recent research, the effectiveness and safety of pharmacological therapy may be correlated with additional genes imp
Topics & Concepts
AripiprazoleAdverse effectMedicineGeneticsBioinformaticsPharmacologyBiologySchizophrenia (object-oriented programming)PsychiatryPharmaceutical studies and practicesPathogenesis and Treatment of HiccupsPharmacovigilance and Adverse Drug Reactions