Litcius/Paper detail

Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells

Kevin Wang, Paulina Coutifaris, David Brocks, Guanning Wang, Tarek Azar, Sabrina Solis, Ajeya Nandi, Shaneaka Anderson, Nicholas Han, Sasikanth Manne, Evgeny Kiner, Chirag Sachar, M.W. Lucas, Sangeeth M. George, Patrick Yan, Melanie Wain Kier, Amy Iarrobino Laughlin, Shawn Kothari, Josephine R. Giles, Divij Mathew, Reem Ghinnagow, Cécile Alanio, Ahron Flowers, Wei Xu, Daniel J. Tenney, Xiaowei Xu, Ravi K. Amaravadi, Giorgos C. Karakousis, Lynn M. Schuchter, Marcus Buggert, Derek A. Oldridge, Andy J. Minn, Christian U. Blank, Jeffrey S. Weber, Tara C. Mitchell, Michael D. Farwell, Ramin S. Herati, Alexander C. Huang

2024Cancer Cell97 citationsDOIOpen Access PDF

Topics & Concepts

Cytotoxic T cellProgenitor cellImmunologyCD8ProgenitorBiologyClonal deletionCancer researchCell biologyImmune systemT cellStem cellGeneticsIn vitroT-cell receptorCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesImmune Cell Function and Interaction