NLRP6 deficiency suppresses colorectal cancer liver metastasis growth by modulating M-MDSC-induced immunosuppressive microenvironment

Liangzheng Chang, Lei Xu, Yuying Tian, Zherui Liu, Meiru Song, Shuang Li, Xinfeng Zhang, Yue Chen, Qiuyao Hao, Yinying Lu, Yunhuan Zhen

2024Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease13 citationsDOI

Topics & Concepts

Tumor microenvironmentMetastasisCancer researchColorectal cancerImmune systemMyeloid-derived Suppressor CellCD8MedicineSuppressorCancerImmunologyBiologyInternal medicineImmune cells in cancerMacrophage Migration Inhibitory FactorCancer Immunotherapy and Biomarkers