Comparative Transcriptomics Identifies Neuronal and Metabolic Adaptations to Hypergravity and Microgravity in Caenorhabditis elegans
Craig R. G. Willis, Nathaniel J. Szewczyk, Sylvain V. Costes, Ingrid A. Udranszky, Sigrid Reinsch, Timothy Etheridge, Catharine A. Conley
Abstract
/FOXO signaling. These data offer a strong foundation from which to expedite mechanistic understanding of spaceflight-induced maladaptation in higher organisms and, ultimately, promote future targeted therapeutic development.
Topics & Concepts
HypergravitySpaceflightCaenorhabditis elegansMaladaptationBiologyWeightlessnessTranscriptomeAdaptation (eye)GeneCell biologyDevelopmental biologyNeuroscienceGene expressionGeneticsAstrobiologyAstronomyAerospace engineeringPhysicsEngineeringSpaceflight effects on biologyGenetics, Aging, and Longevity in Model Organisms