Microfluidics-aided fabrication of 3D micro-nano hierarchical SERS substrate for rapid detection of dual hepatocellular carcinoma biomarkers
Changbiao Zhan, Zihao Guan, Liandong Yu, Tongmei Jing, Huakun Jia, Xiaozhe Chen, Rongke Gao
Abstract
, respectively, which represents a good response. Indeed, this platform is easy to fabricate, of low cost and has short detection time and comparable detection limits to other methods. As far as we know, this is the first study to achieve the simultaneous detection of AFP and AFU on a microfluidic platform. Therefore, we proposed a new simultaneous detection platform for dual HCC biomarkers that shows strong potential for the early diagnosis of HCC.
Topics & Concepts
MicrofluidicsNanotechnologyFabricationMicrofluidic chipSubstrate (aquarium)Hepatocellular carcinomaMaterials scienceNano-Cancer researchBiologyMedicinePathologyEcologyAlternative medicineComposite materialGold and Silver Nanoparticles Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection