2α-Hydroxyalantolactone from Pulicaria undulata: activity against multidrug-resistant tumor cells and modes of action
Mohamed‐Elamir F. Hegazy, Mona Dawood, Nuha Mahmoud, Mohamed Elbadawi, Yoshikazu Sugimoto, Sabine M. Klauck, Nagla Mohamed, Thomas Efferth
Topics & Concepts
BiologyCell cycle checkpointCell cycleTranscriptomePI3K/AKT/mTOR pathwayDownregulation and upregulationBlotMultiple drug resistanceCytotoxicityMolecular biologyApoptosisSignal transductionGene expressionCell biologyBiochemistryDrug resistanceGeneMicrobiologyIn vitroSesquiterpenes and Asteraceae StudiesPlant Toxicity and Pharmacological PropertiesFungal Biology and Applications