Dinuclear zinc-catalyzed asymmetric [3 + 2] cyclization reaction for direct assembly of chiral α-amino-γ-butyrolactones bearing three stereocenters
Wenpeng Yang, Shi‐Kun Jia, Tiantian Liu, Yuan‐Zhao Hua, Min‐Can Wang
Abstract
A highly atom-economic and novel enantioselective [3 + 2] cyclization reaction for the construction of optical α-amino-γ-butyrolactones possessing three stereocenters.
Topics & Concepts
StereocenterChemistryEnantioselective synthesisCatalysisZincStereochemistryAmino acidOptically activeAtom (system on chip)Combinatorial chemistryOrganic chemistryBiochemistryEmbedded systemComputer scienceAsymmetric Synthesis and CatalysisAxial and Atropisomeric Chirality SynthesisTraditional and Medicinal Uses of Annonaceae